Monday, October 27, 2008

McCain and Obama on drug policy

The Fort Wayne News-Sentinel reports on Obama's and McCain's positions on drug policy.

Addiction Inbox also has posts on both candidates.

Bottom line: McCain wants to continue the drug war and Obama wants to promote drug courts and alternatives to incarceration.

Saturday, October 25, 2008

Things that make you go, "hmmm"

From Alcohol and Alcoholism:
Aims: Attention-deficit/hyperactivity disorder (ADHD) is of great clinical importance not only because of its high prevalence but also due to the frequent comorbid illnesses that are connected with this disorder. Several studies were able to demonstrate that ADHD constitutes a significant risk factor for the exacerbation of habit-forming illnesses, i.e. addictions. Methods: We conducted a study on 152 adult patients with alcohol dependence (n = 91) or multiple substance addiction (n = 61) to determine whether or not these patients were affected by ADHD. For retrospective assessment of childhood ADHD, the WURS-k was used as well as the DSM-IV symptom checklist for ADHD. The CAARS was used to assess the persisting symptoms of ADHD in adults. Results: 20.9% (WURS-k) or 23.1% (DSM-IV diagnostic criteria) of the alcohol-dependent patients showed evidence of retrospective ADHD affliction in childhood. With the help of CAARS, ADHD was proved to be persistent in 33.3% of the adult patients. In the group of substance-addicted patients 50.8% (WURS-k) and 54.1% (DSM-IV) presented with diagnostic criteria for ADHD in childhood and 65.5% (CAARS) showed evidence of ADHD persisting in adulthood. Conclusions: These results reveal that habit-forming illnesses can be associated with a high comorbidity with ADHD, expressed in the form of alcohol abuse and also in consumption of illegal drugs. The results underline the great importance of early and adequate diagnostics and therapy of ADHD for the prevention of habit-forming illnesses.
What I find remarkable is not the co-occurrence of ADHD and AOD problems. Rather, that this finding is accepted, and a finding of high intelligence among people with alcohol problems is met with such skepticism. What does this say about the researchers? What questions are they not asking, or at least taking seriously? Is this a case of the ladder of inference at work?


Narcotic Farm

From Scientific American:

From 1935 to 1975, just about everyone busted for drugs in the U.S. was sent to the United States Narcotic Farm outside Lexington, Ky. Equal parts federal prison, treatment center, research laboratory and farm, this controversial institution was designed not only to rehabilitate addicts, but to discover a cure for drug addiction.

...the institution became a premier center for research into drug addiction and treatment, advancing everything from the use of methadone to treat heroin withdrawal to drugs that blocked the action of opiates. Along the way, Narco was frequented by legendary jazz musicians such as Chet Baker and Sonny Rollins, as well as actor Peter Lorre and beat generation writer William S. Burroughs, who recounted his experience in his first novel, Junkie.

The documentary also chronicles how the Farm was shut down when Congress discovered that researchers there were using patients as human guinea pigs in CIA-funded experiments into LSD. Drug research on federal prisoners is now illegal.

Still, the filmmakers note accomplishments at the institution remain milestones in addiction science and treatment. Its most important contribution might be how it transformed the way society views addicts—"as people suffering from a chronic, relapsing disorder that affects public health," says book co-author Nancy Campbell, an associate professor at Rensselaer Polytechnic Institute in Troy, N.Y., who studies the history of drug addiction research.

About the lower image:
The original caption for this photo, which appeared in a 1951 New York World-Telegram & Sun series on the Narcotic Farm, read: "This desperate narcotics addict, caught like his fellows in the revolving door of law enforcement, will probably go back to his habit when he is free."
Complete slide show here.

Info on the film here.

Info on the book.

UPDATE: The original article has since issued the following correction:
Correction (posted October 25, 2008): When originally posted, this story suggested that a Congressional investigation into the Narcotic Farm had led to its closure. In fact the main reason Narco was closed was that its centralized form of institutional care was supplanted by a national network of local treatment centers. Its closure coincided with the Congressional investigation into LSD research. Scientific American regrets the error.

Friday, October 24, 2008

Local policy news

The Ann Arbor News suggests that they would like to endorse a medical marijuana proposal, but this one isn't it.

Thursday, October 23, 2008

"unexpected findings"

I don't attribute a lot of significance to this, but I find it amusing that they state 3 times in this very brief press release that these findings are contrary to their expectations. It just CAN'T be true. Further examination is need.
NEW YORK (Reuters Health) - Contrary to expectations, higher intelligence scores at age 10 may be associated with higher levels of alcohol intake and alcohol-related drinking problems during adulthood, study findings suggest.

Moreover, these associations appear "markedly stronger among women than among men," Dr. G. David Batty, from the University of Glasgow in Scotland, and colleagues report in the American Journal of Public Health.

However, "given that these findings ran counter to our expectations," the investigators call for further examination of this relationship.

Batty's team assessed associations between mental ability scores obtained when 8170 boys and girls were 10 years old and their alcohol intake and alcohol problems when they were about 30 years old.

Of the 3895 men and 4148 women who reported drinking alcohol as adults, those with higher average scores on childhood mental ability tests were also more likely to have indications of alcohol problems in adulthood.

The association between higher mental ability in childhood and adulthood problem drinking became stronger among women than among men after allowing for socioeconomic factors such as social class during both childhood and adulthood.

Specifically, for every 15-point increase in childhood mental ability score, the likelihood of drinking problems increased 1.38 times for women, and 1.17 times fro men

These unexpected findings, and the lack of other research in this area, indicate the need for "further examination of the relation between childhood IQ and adult drinking patterns," the investigators conclude.

SOURCE: American Journal of Public Health, October 2008
[Thanks Jess]

Monday, October 20, 2008

Local sentencing sense

The Ann Arbor News reports on the Washtenaw County Sobriety Court and our friend Judge Creal:
The defendant, who had been arrested for drunken driving, stood before 15th District Judge Julie Creal.

But unlike a typical sentencing, Creal asked questions of a more personal nature - wondering whether the death of a relative would impact the man's sobriety.

"I'm dealing with it," he said. "It's a tough time for me."

Creal asked how long he'd been sober.

"Sixteen months sober on Tuesday," he replied.

The nearly two dozen people stuffed in Creal's small courtroom for Washtenaw County's Sobriety Court broke into applause.

"Fabulous," Creal said as she clapped.

A judge who applauds? A group of defendants cheering each other's successes?

That's Sobriety Court, created by Creal four years ago to help repeat drunken drivers get treatment. Representatives from the prosecutor's office, city attorney's office, law enforcement and probation department also are present.

People who enter a voluntary, 18-month program and successfully complete it can avoid jail time and save about $1,000 in fines and fees. The program includes random testing at home, attendance at 12-step meetings, making small payments and staying sober.

Since it started, 157 people have entered the program. Of those who are no longer in the system, 60 have completed it successfully - a rate of about 76 percent.

The focus of the program is really about owning up to a problem.


I posted last week about how drug courts and health professional recovery programs are leading the way for the rest of us.

Methadone maintenance as palliative care

David Clark sticks his neck out on MMT:
As I have said many times before, I have nothing against methadone substitution therapy per se, but I feel strongly about it being used with clients being offered no, or only minimal other, support. I have written:

'Due to the approach adopted by much of the UK treatment system, this generally leads people from one addiction to another without providing a realistic opportunity to attain recovery.

Whilst methadone (and Subutex) have an important role to play in helping people take the chaos out of a heroin-using lifestyle, they should not be prescribed in isolation or with minimal other support.

The majority of heroin users actually want to get off drugs completely, not be “left” long-term on methadone or other substitute drugs. They must be provided with the choice of, and help in, finding a path to recovery, rather than just being helped to live with addiction. Much of the treatment system shows a shocking paucity of ambition for its clients. If cancer patients were only offered what amounts to a form of palliative care, it would be seen as a scandal.'
This issue of palliative care gets to the very crux of the issue doesn't it?

From Wikipedia:
The term "palliative care" may be used generally to refer to any care that alleviates symptoms, whether or not there is hope of a cure by other means;
It really comes down to whether once believes addiction is a treatable illness doesn't it?

I'd add that it might be possible for a methadone program to have a recovery orientation, rather than a palliative orientation, but it's not what I see.

Once again, I'd welcome a day when addicts are offered recovery oriented treatment of an adequate duration and intensity and have the opportunity to choose for themselves.

Sunday, October 19, 2008

Transformed...beyond hope

What is there to say?
The NAOMI study was funded by an $8.1-million research grant from the Canadian Institutes of Health Research.

The heroin and hydromorphone participants received three doses a day from health-care professionals in downtown clinics. Most participants - 192 - were from Vancouver. Fifty-nine were from Montreal.

After one year, 90 per cent of the addicts being provided heroin were still in the program and 54 per cent in the methadone program remained - much higher than the retention rates for conventional treatment, Dr. Schechter said.

Researchers said they found a decrease in criminal activity and use of street drugs, and an improvement in health among participants.

Participants must have been addicted to heroin for at least five years and attempted treatment twice in the past.

"This is a group that society has written off as beyond hope," Dr. Schechter said.
Once again, Emerson comes to mind:
This conformity makes them not false in a few particulars, authors of a few lies, but false in all particulars. Their every truth is not quite true. Their two is not the real two, their four not the real four ; so that every word they say chagrins us and we know not where to begin to set them right.
Two failed treatments and the best we can hope for is reduced crime, some improvements in health and persistence in showing up to receive free heroin? All for only $32,270 per participant?

Friday, October 17, 2008

Spirituality and recovery

Martin Nicolaus notices a not yet published study on the impact of spiritual guidance as part of treatment. There was no impact. In fact, the group with spiritual guidance by certified spiritual directors had worse outcomes on measures of depression and anxiety, though a group receiving spiritual guidance from their counselor did just as well as the other groups.

What's especially interesting about this study is that Bill Miller, the lead author, is very friendly to spirituality as an tool for facilitating change. He seems stumped but isn't questioning the study itself.
There is reason for confidence in the findings of this study. Outcome variables were carefully measured by independent interviewers, fidelity of interventions was good, and 82% of all possible follow-up interviews were completed. The studies were powered to detect a medium between-group effect size that would be sufficiently large to be of clinical interest ([Cohen, 1988] and Miller and Manuel (in press) Miller, W. R., and Manuel, J. K. (in press). How large must a treatment effect be before it matters to practitioners? An estimation method and demonstration. Drug and Alcohol Review.Miller and Manuel (in press)). Null findings were replicated across two study designs, and the direction of differences was, in many cases, opposite to prediction. We thus found no evidence for a beneficial effect of this spiritual counseling approach during the acute phase of addiction treatment. Different and more intensive spiritual counseling might increase daily spiritual practices, spiritual experience, and meaning and thereby influence substance use outcomes. Given the magnitude of changes that occur in early recovery, however, we believe that a more promising approach is to focus on spiritual development after a period of stabilization in which other basic needs have been addressed. Within a long-term care perspective, spiritual direction may fit better in later recovery, with a goal of maintaining and broadening the initial gains of sobriety.
It would be interesting to see more research on spirituality and recovery. I'm inclined to believe that spirituality can be a useful therapeutic tool. If nothing else, for people when enter treatment with spiritual beliefs, it might be used to increase engagement and participation in treatment. It might also be used as a long term source of support for change. (We do value a holistic approach, right?)

Along the lines of a stage dependent model, as Miller suggests, Project SAFE reported that many of the African American women in the study initiated their recovery in 12 step groups and sustained their recovery in churches.

The study said nothing of the participants' predisposition to spirituality. That seems important to me.

Other questions that might be interesting include:
  • What forms of spirituality are helpful or unhelpful? Some clearly emphasize a stronger internal locus of control while others emphasize an external locus of control.
  • Can helpful elements of the helpful forms of spirituality be unbundled?
  • What are the non-spiritual paths to those helpful elements?
  • There is a persistent assumption that all clients will benefit from spirituality. Is this true? Are these some who might benefit, others who are unaffected and some whose treatment outcomes are harmed?
  • Along the lines of Miller's thinking, to what degree are these responses stage dependent?
DF employees - let me know if you want a copy of the study.

Thursday, October 16, 2008

Early Exposure to Drugs and Alcohol

Interesting findings about the relationship between early substance use and troubled kids. It tries to answer whether substance use creates troubled kids or troubled kids engage in early substance use.
First, the prior consensus in child psychology and psychiatry has been that adolescents who go on to develop substance dependence are not normal adolescents who are experimenting with substances, but rather are highly likely to be adolescents with a prior history of conduct problems (Armstrong & Costello, 2002). If this is the case, the documented association between early substance exposure and adult outcomes would not be due to exposure per se, but instead would be the result of who is exposed (Wells, Horwood, & Fergusson, 2004). Prior research has not resulted in a consensus regarding the causal status of substance exposure (Agrawal, Neale, Prescott, & Kendler, 2004; Kandel, 2003; Lynskey et al., 2003; Prescott & Kendler, 1999). However, results from this study are consistent with a causal effect of early substance exposure among adolescents with no prior history of conduct problems. That is, early-exposed adolescents with no conduct-problem history, although they did not have an increased risk of failing to complete school, were more likely than their matched non-early-exposed counterparts to develop substance dependence, test positive for herpes, have an early pregnancy, and be convicted of criminal offenses.

Second, findings from this prospective study support a causal link between early substance exposure and a wide range of adult outcomes. Propensity-score-adjusted effects indicate that early substance exposure more than doubles the odds of adult substance dependence, herpes infection, early pregnancy, and criminal convictions.
Strangely, CADCA explains the study by describing some subjects as good kids and the others as bad kids.

[hat tip: Jess]

More on Methadone

My recent post on methadone prompted several comments, some making really great points. I decided to post all of them so that they would not be missed. The last 4 comments are great, you can guess what I think of the first 2.
OpenID armme said...

Your still working on the idea that addiction is some spiritual malady. Your way of thinking is in the DARK AGES, my friend. Your idea of recovery will soon be a thing of the past. It will be like performing an Exorcism on mental illness...once thought to be the ONLY form of treatment, but now considered completely irrational.

Your still trying to stop drug use...when you should be focusing how to get the addict to live a better life. Your treating an illness of endorphin dysfunction by taking away the only thing that corrects that dysfunction with stability.

You can continue to offer people your "exorcism approach" or you can learn the science behind opiate addiction and realize stopping people from using drugs doesn't stop the disease.

Do you want to treat the disorder so these people can have a better life--or do you just want them to stop using drugs no matter HOW miserable they have to be to do so?

Sometimes, MANY TIMES, you can't have both. Not with opiate addiction.

Anonymous Anonymous said...

"counseling", while possibly helpful to some who may need referrals to things like job training, childcare, housing options, etc, is NOT the answer to most hardcore addiction problems. Science has shown clearly that addiction is a brain disease, a disruption of the brain chemistry. That is not something you can repair with a few hours of talk therapy. If talk therapy (or meetings or group therapy) worked even fairly well for addiction, there would have been no need to come up with something else to treat it--but it didn't and doesn't. We don't treat ANY other legitimate disease this way. People with schizophrenia, bipolar disorder, clinical depression, etc--all brain chemistry disorders--may receive some therapy sessions but it is almost always in conjunction with MEDICATION, which does the actual work of repairing and restabilizing the brain. Why should addiction be treated differently--especially when it has been clearly shown that abstinence based treatment has an extremely low effectiveness rate for addicts and particularly for opiate addicts?

Anonymous Anonymous said...

As a recovering IV addict for more than 35 years, I continue to be appalled by these guys who push needles, methadone maintenance, etc. with their well-meaning efforts to "help us." Thankfully, none of you were around when I got clean - only people who assured me that I could in fact get clean and live a happy life.

The expectation that people like me are largely unable to find lasting clean time undermines our chances - and makes the way for the "experiments" by psychiatrists and others - naltrexone, methadone (now at new and much high doses!), acamprosate - hell, the Chinese drill out our limbic system with a Makita.

The lie is exposed - we CAN recover.

Anonymous Anonymous said...

I too am a recovering IV user. I had the experience of being on maintenance several times and also of doing 21 day methadone detoxes in California a few times. My experience when I was using was that every time the methadone kicked in, the urge for CRACK became overwhelming. My problem is that I am a drug addict who has an allergy to drugs. When I get drugs in my system I want more and more and more. There is not enough methadone in the world to make me happy, or to fix whats wrong with me. I could drink a ton of methadone and be close to death but still be crawling across the floor trying to find more drugs. It doesn't work for me. Recovery after many years of using and living the lifestyle was not easy, but it did get better, and the alternative was way worse. I am SO glad that I was introduced to a program of abstinence based recovery and that the system did not give up on me by relegating me to a methadone clinic for the rest of my life. I am also quite sure that my family, the courts and everyone else on the road is glad as well. Recovery has changed my life!

Anonymous Anonymous said...

You are SPOT ON in describing the "study" practices of those who want the world to believe that methadone is a miracle. Thanks for stating it this way.

The belief that methadone maintenance has a higher success rate than abstinance-based treatments is another huge lie these people use. They want to compare the people taking methadone to the people who have tried abstinance, without holding the same goals for each method. The maintenance population as about a quarter of the success rate at remaining abstinant as the other group after leaving mmt.

I personally think that nearly every sample used in these studies has a bias, and it is meant to be that way. The people conducting these "studies" have something to sell, and I think people should keep that in mind. It's little more that advertising in a free market economy, IMO...

Anonymous Dr Dave said...

Nice critical appraisal of another tired study that does not help move things on at all. I couldn't agree more that low expectations of what opiate addicts might achieve is fundamental in ensuring that they don't achieve more.

I'm a doctor who is also a recovering opiate addict. At no point was methadone suggested as a treatment choice (apart from detoxification). The expectation was that I would recover with the right sort (and duration) of treatment. Now I adopt the same high expectation of my heroin addicted patients. They get better and stay better in the main. Our service is filled with reovered addicts who infectiously pass recovery on to their peers. Okay, so my recovery capital is arguably much higher, but we can increase the chances of success with some simple interventions (linking into recovery communities, providing housing and employment solutions, giving aftercare and long term management plans which focus on the client self-managing). We do it. It works. People get better.


Wednesday, October 15, 2008

Gone, baby, gone

It appears that opium harvests greatly exceed demand for heroin and no one seems to know where the excess heroin is.

More sentencing sense

I mentioned drug courts in a recent post. Well, the NY Times is reporting on drug courts.

Highlights:
Clearly, the courts do not help everyone. One of the most successful programs is in New York State, where about 1,600 offenders are in adult drug courts. Studies found that while 40 percent dropped out of the program along the way, those who started it, including both dropouts and graduates, had 29 percent fewer new convictions over a three-year period than a control group with similar criminal histories and no contact with drug courts, Mr. Berman said.

In other regions, half or more of those who start the program do not finish. And recidivism rates for participants are reduced by about 10 percent to 20 percent, depending upon the quality of the judges and treatment programs, said John Roman, a researcher at the Urban Institute, based on a recent study.

An earlier review of 57 “rigorous” drug court evaluations around the country, led by Steve Aos of the Washington State Institute for Public Policy, found that recidivism was reduced on average by only 8 percent, but with wide variation.

Yet even that modest reduction in crimes and prison yields cost benefits. The report this year by the Urban Institute found that, for 55,000 people in adult drug courts, the country spends about half a billion dollars a year in supervision and treatment but reaps more than $1 billion in reduced law enforcement, prison and victim costs. A large expansion would yield similar benefits, the report argued.

But some scholars, like Mark A. R. Kleiman, director of the Drug Policy Analysis Program at the University of California, Los Angeles, remain skeptical about the potential and the achievements. He suggests, for example, that success rates of some courts may be inflated because they take in offenders who are not addicted and entered this track only to avoid prison. Dr. Kleiman advocates a slimmed-down system that does not initially require costly treatment, as drug courts do, but simply demands that offenders stop using drugs, with the penalty of short stays in jail when they fail urine tests. Such an approach has shown promise with methamphetamine users in Hawaii, he said, and because it is far cheaper, it can be applied to far more offenders.
I'd like Kleiman's proposal if what he describes is a "pre-drug court" that would step addicts up into a full drug court.

There's something exciting and troubling about drug courts and health professional recovery programs in the context of the addiction treatment system. Exciting because there are important ways that they are succeeding in implementing some chronic disease management elements, namely long term monitoring and swift reintervention when relapse happens or appears imminent. Troubling because it seems that we are only implementing these strategies with involuntary involuntary clients and other systems are the ones implementing these programs for their own ends. (Not that there's anything wrong with this. In fact, it's great that these systems are approaching these problems in this way. But it should be cause for concern that these other systems are pulling us in this direction rather than us leading the way.) These programs get to be considerably more directive with these patients--they HAVE to go to treatment, they HAVE to get regular drug testing, they HAVE to attend recovery support groups, etc.

There will be a whole new set of challenges with voluntary clients. I suppose we'll face the same challenges that cardiac care and diabetes programs face every day.

How methadone research works

Start with the premise that opiate addicts don't get well. (Unless they're doctors.)

Perform a study offering only two variations of your preferred treatment. (Cheap and crime reducing.) One is high dose or long duration and the other low dose or short duration. Do not offer a recovery oriented option at all, or offer a recovery oriented option of inadequate duration and intensity.

Find that, when offering 2 lousy options, the lousy option with the longer duration or higher intensity reduces symptoms better at follow-up.

Run a headline of, "Methadone Detoxification Remains No Match for Methadone Maintenance, Even with Minimal Counseling." In the comments, declare, "Methadone maintenance is the preferred treatment approach for heroin dependence."

Bonus: "No difference between groups was found for cocaine use or depressive symptoms."

Bonus bonus: "Results for MM with standard counseling (2 hours a month) did not differ from those for MM with minimal counseling (15 minutes a month)."

Question: Do you think this will be used to justify offering even less counseling to methadone recipients?

UPDATE: I got some grief on this post. Here's my response:

Five points:
  • First, a question. If methadone is a superior treatment option, why don't they use it for opiate addicted health professionals? Health professionals have high rates of opiate addiction and typically receive long term treatment with monitoring that lasts several years. Treatment is stepped up or down as needed. Guess what? They have great treatment outcomes. You might be inclined to chalk it up to a population with lots of recovery capital. To be sure, that plays a role, but surely a real chronic disease management approach plays a role too. 
  • Second, is it coincidence that this study was done on poor black men? Why aren't studies like this done on young adults from affluent communities?
  • Third, methadone used to be one component of some comprehensive bio-psycho-social treatment programs. I understand that there are still some programs that fit this description, but every program in my area is a dosing clinic and little more.
  • Fourth, regarding misery, notice that there was no difference in depressive symptoms. 
  • Fifth, heroin addicts in our long term programs do just as well as everyone else. It's all about hope and expectations. Beware of the subtle bigotry of low expectations.
All I want is a day when addicts are offered recovery oriented treatment of an adequate duration and intensity. I have no problem with drug-assisted treatment being offered. Give the client accurate information and let them choose.

Tuesday, October 14, 2008

What's possible

One Colorado community is taking the bull by the horns and adopting a 0.25% sales tax to establish a community detox and treatment services.

By the numbers
Larimer County Issue 1A on the November ballot would levy a 0.25 percent sales tax - or 25 cents on a $100 purchase - to build a facility that would provide treatment for people with mental-health and substance-abuse problems. Below are preliminary figures tied to the proposal:

> $12.5 million: Cost to build the facility
> $5.8 million: Staffing costs for new programs
> $1.3 million: Staffing costs to expand existing programs
> $750,000: Annual medication costs
> $350,000: Annual maintenance and utilities costs
> 41,000 square feet: Size of the building
> 1,200: People who would be served each year
> 72: Staff
An impressive vision. This is a county of 250,000.

Drug Czar = pointless, feckless, hopeless

The post of Drug Czar has become the very model of a modern major waste of time--a pointless, ineffective, reactionary bureaucratic construction.

Maybe it will become a verb, as in, "I've been Drug Czarred!"

Monday, October 13, 2008

Rats, cocaine, memory and volition

From Scientific American:
Scientists know that addictive drugs can mess with the brain’s circuitry and hijack its reward systems, but a July 31 rat study in the journal Neuron shows that psychological factors may be more instrumental in causing these changes than a drug’s chemical effects are. Cocaine use triggers long-lasting cellular memories in the brain, the study found—but only if the user consumes the drug voluntarily.

A team led by Billy Chen and Antonello Bonci, both at the University of California, San Francisco, trained three groups of rats to press levers that delivered cocaine, food or sugar. The researchers injected cocaine into a fourth group. When they examined the rats’ brain tissue, they found an increase in synaptic strength within the reward center in those rats that had self-administered sugar, food or cocaine. These cellular memories were short-lived in the sugar and food groups, but in rats that had self-administered cocaine they persisted for up to three months after consumption had stopped. Most interestingly, the brains of rats that had consumed cocaine involuntarily did not show such imprints.

The findings illustrate that the pharmacological effects of cocaine alone are not enough to create reward-associated memories, Bonci says. “Instead the motivation for taking the drug seems to be a key component in the process as well.”

The team is working to find ways to remove the long-term cellular memory left by voluntary cocaine use, which eventually could help treat addiction in humans by taking away the desire to actively seek the drug, Chen says.
I posted on this before, but missed this important finding--that the rats involuntarily receiving cocaine did not develop these memory imprints.

This is weird. Kind of ironic that volition had to be exercised for the deterioration of volitional control.

Can lab rats become addicted through involuntary cocaine consumption? Or, they just won't develop these imprints? Also worth noting is that behavior extinction had no impact on these cellular memory imprints.

Brain scan skepticism

I've had a gnawing fear that the brain scan research of the last two decades that has been used to support the disease model will be discredited by some new innovation in technology, or the realization that everything lights up the brain like the scans we're frequently shown. (I don't believe this, but I worry about it from time to time.)

Good news. This article by a brain scan skeptic says nothing that concerns me.

Sentencing sense

The Washington Post reports that the U.S. Sentencing Commission is considering recommending some common sense on drug crime sentencing.

Astonishingly, the article fails to put the import of this in its proper perspective.









Given the state of American drug policy debates, drug courts seem to be the most pragmatic path to ending this insanity. There may come a day when we make more radical changes in drug policy, but, for the time being, drug courts balance concerns about public safety, drug control and the wanton incarceration of people whose primary crime is being an addict.

Thursday, October 09, 2008

The future of treatment spending

Health Affairs looks at the future of substance abuse treatment spending. The future looks pretty grim:
Growth in SA spending is forecasted to average 5.0 percent between 2003 and 2014, slightly faster than the rate of 4.8 percent in the 1986-2003 historical period. Over the next decade, SA spending growth is expected to continue to increase at slower rates than MH health spending, mainly because pharmacotherapy, which has driven increases in MH spending, currently plays only a small role in SA treatment. This is expected to result in an SA share that falls from 1.3 to 1.0 percent of all-health spending. Moreover, growth in SA spending increases at a slower pace than growth in the economy, with the SA share of GDP falling slightly between 2003 and 2014.
Some of the analysis is already a bit dated, give the recent passage of parity legislation:
Historically, a dominating characteristic of private SA spending has been the lack of funding increases from private health insurance, which declined an average of 1.6 percent annually between 1986 and 2003. We expect private insurance SA spending growth to accelerate somewhat during the projection period--to 1.3 percent annually. However, actual spending in 2014 is anticipated to be below that estimated for 1986, and the private health insurance share of SA spending is expected to continue falling (from 10 percent in 2003 to 7 percent in 2014). Barriers to SA insurance coverage exist that are not present in medical/surgical coverage, including annual and lifetime limits for inpatient hospital stays and outpatient visits, and higher cost sharing through deductibles and coinsurance.
Specialty treatment settings are increasingly relied on as a share of spending, but, anecdotally, this makes no sense. Specialty treatment settings are disappearing and McClellan has documented the instability of the treatment system, including high rates of program closure. The definition for SSACs must be pretty inclusive.
Specialty SA centers (SSACs) have emerged as major providers in the delivery of SA treatment, with spending for their services increasing from 19 percent of SA spending in 1986 to a projected 42 percent in 2014. SSACs are multidimensional facilities that deliver services ranging from outpatient care to residential services. Programs can include those targeted to special populations (for example, people with HIV/AIDS or opiate addictions). SA spending on treatment in SSACs is forecasted to increase at a 5.3 percent average annual rate over the projection period, similar to the overall SA annual growth rate between 1993 and 2003.

Spending for SA hospital treatment fell from 48 percent of SA spending in 1986 to 24 percent in 2003, where the share is expected to remain in 2014. SSACs likely supplied the outpatient treatment venue for people who previously would have been treated in expensive hospital settings.
Parity has been passed since this paper was written and it's likely a lot more will change by 2013. It seems likely that some sort of universal coverage be enacted in the next 5 years and we can hope that decent addiction treatment will be covered.

Tuesday, October 07, 2008

Insite saves two to 12 lives a year, study says

Saving lives is important.

How many more lives would be saved adding recovery-oriented treatment on demand? How many more lives would be restored? Is Insite lobbying for the addition of these services?

It doesn't have to be either/or. It can be both/and.

Rhythms of despair

Provide poor/inadequate abstinence-oriented treatment ==>

Poor prognosis: client fails ==>

Conclusion: these people can't recover ==>

Organize treatment system and research around belief that addicts won't recover ==>

Public and helpers despair at the impotence of the system ==>

They look to research for answers, but research is organized around the assumption that addicts can't recover ==>

They reject the treatment system and the addict:
Street drugs are a lifestyle choice. Being a taxpayer is not; and it is harder to be tolerant of the rotten choices of others when one's hard-earned money is spent subsidizing them long-term.

The latest in harm reduction

Email goggles.

Some unknown circle of hell

The Washington Post runs a heartbreaking account of a parent trying to get help for Nicole, her heroin addicted daughter. Well worth the time to read.

Parity will mean that families with insurance will be able to access treatment but the insurer will implement restrictive protocols for accessing more expensive forms of treatment, like inpatient and residential.

[via dailydose.net]

Monday, October 06, 2008

Win the drug war?

Margret Kopala argues that the war on drugs is working. She points to a recent U.N. report, alcohol prohibition in the U.S., and Sweden's drug policy.

No doubt prohibition reduces drug use. The important question is, at what cost? We decided that the costs of alcohol prohibition were greater than our commitment to it could sustain.

The cost for the current drug war in the U.S. is high. I'm not an advocate of legalization, but any sensible person has to ask questions like:
  • How can we mitigate the human costs associated with the war on drugs?
  • What are we not doing, because we're investing enormous capital and energy in the war on drugs?
  • Are there other strategies that might be effective in trying to achieve our goals?
  • Are our goals realistic?
Further, Ms. Kopala resorts to characterizing supporters of harm reduction as part of a medical industrial complex. This suggests that HR advocates operate from bad motives. I disagree with many of them vigorously on many issues, but in most cases, their motives are good. (Just as advocates of recovery oriented systems of care are not zealots, pleasure police or motivated by moral panic.) However, their motives are rooted in an ideology that harms addicts in some ways (By lowering expectations and nurturing pessimism about prospects of recovery.) and has benefited addicts in other ways (Challenging the rest of us to work with active addicts, pay more attention to preventing illness and lower thresholds to receiving help.).

She's be more persuasive if didn't ascribe bad motives to those on the other side of the argument. Also, I get the impression that Sweden's policy has been successful. What are the challenges in replicating this policy elsewhere? What are the initial steps? Rather than tossing it off as a defense of the drug war status quo, how do we get there?
UPDATE: A reader appropriately took me to task for overlooking this
Nils Bejerot ... challenged the view ... that addiction was a health problem. ... Bejerot's argument that addiction was a learned behaviour made possible by the availability of drugs, time, money, user role models and a permissive ideology. This behaviour could be "unlearned," he said ...
She's right. It's absurd. Ideology is a problem on both sides of the street. It'll be nice when we manage to beyond this false dichotomy.

Friday, October 03, 2008

Parity passes

Parity finally passed both branches of congress and was signed into law by the President.

This is a good and important step. Health Affairs explains what this means, what will happen next and what still needs to happen:
A thoughtful essay by Audrey Burnam and José Escarce in an earlier volume of Health Affairs contends that the debates around parity in insurance benefits are the latest manifestations of a longer-standing policy issue regarding equity of mental health care relative to general medical care. These authors argue that in an era of managed care, benefit parity is an insufficient mechanism for ensuring equity for those with a mental illness.26 Put another way, full benefit parity is an important "sequential" step toward the broader goal of ensuring that persons with a mental illness or addiction have the same opportunities for seeking and receiving appropriate treatment as those with a physical illness.

Importantly, a sequential approach to promoting treatment equity implies a recognition that full parity resolves some, but far from all, obstacles to access and use of appropriate services among persons with mental and addictive disorders. On the supply side, full parity generally indicates a nominal expansion of benefits. However, parity also has yielded increased management of care, and such management can be differentially applied in ways that produce unequal treatment opportunities (through either initial access or intensity and/or duration of services) for those with psychiatric versus general medical conditions. On the demand side, full parity results in the removal of arbitrary and inequitable limits to treatment. However, removal of these limits under parity may have little effect on the concomitant stigma that keeps many who need mental health and substance abuse services from seeking such care. In short, legislating full parity will promote, but not achieve, treatment equity for those with mental and addictive disorders. Nevertheless, without such action, the goal of equity will continue to remain elusive.

Wednesday, October 01, 2008

Recovery and stigma

SAMHSA did a survey of attitudes toward addiction and recovery. The press release paints a very optimistic picture, but the full report tells me that we have a long way to go.

30% of respondents said they'd think less of a friend with a drug problem and 18% said they'd think less of a friend in recovery. 66% said that they would be comfortable being friends with someone in recovery, 63% would be comfortable working with someone in recovery and 57% would be comfortable living next door to someone in recovery.

I'm not sure how to feel about this, but I suspect we're supposed to be thrilled. I don't find it very encouraging. Polls about attitudes toward gay people offer more optimistic numbers for gay rights activists and they still face considerable stigma and ballot initiatives in every election cycle.

I understand that this kind of process is important, but I sort of resent people even being asked whether they are comfortable with me. I don't really care if they're comfortable with me. What I do care about is whether they are willing to extend community help and support to the addict who is still suffering. Clearly, we're not there.

I also want to normalize recovery just as much as the next guy, but I'm a little worried that our advocacy of recovery may inadvertently reinforce stigma against active addicts by emphasizing, "We're in recovery! You have nothing to fear from us." As a person in recovery, I don't need anyone's acceptance and I wonder if promoting recovery is really the best way to soften attitudes toward active addicts.

Some of the more troubling findings included that about 40% respondents believe that addicts and alcoholics had only themselves to blame and 42% believe that illicit drug addicts can't recover.

I'm not sure what to make of the prevention attitudes. I suspect SAMHSA finds them encouraging, but I assume that they are more symptomatic of the belief that addiction has a lot to do with a person "losing their way", "getting hooked", or falling in with the wrong crowd."

One more question (to add to the meandering nature of this post). How might current efforts to define "recovery" in a specific, yet inclusive way, affect social attitudes toward addicts?

Okay, another question. Are the motivations to include non-abstinent addicts as "recovering" inclusive compatible with neurobiology and the stigma reduction agenda?